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Biomedical Science and Technology

  • Inicio

    Director

     

    Prof. Manuel Desco Menéndez

     

     

    About the program

     

    In recent decades, the interdisciplinary field of bioengineering and biomedicine has experienced an explosive growth, accompanied by an unprecedented development of new technologies, many of which have originated from the interaction between engineers and biomedical professionals.

    This has led to the need for a multidisciplinary approach to the research, development and production of biomedical products, thus opening employment opportunities for new professionals, particularly those with a multidisciplinary doctoral training like the one mentioned above. Some examples are emerging fields such as tissue engineering, reagents and electronic devices for medical diagnosis, advanced biomedical imaging tools, 3D bio-printers, devices based on microfluidics and nanotechnologies, or the application of 'big data' or machine learning to solve biomedical problems.

    This Ph.D. program is a response to this need for specific training in the field of bioengineering and biomedicine. Specifically, the program aims at providing students with an adequate base in biomedical technologies that enables them to find innovative solutions to biomedical problems by combining experimental methodologies typical of life sciences with computational and technological methodologies specific to engineering.

    Graduates in this program can practice their profession in either public or private research centers, or in a wide variety of industries in the biomedical area (devices, diagnostics, pharmaceuticals, biotechnology, pharmacy, etc.) and in electromedicine, as well as in through entrepreneurship and the creation of new companies.

    Given the marked multidisciplinary nature of the program, the profile of prospective students is very broad, and covers both master's degrees in engineering disciplines and biomedicine.

     

    • Ph.D. program under regulation RD 99/2011, January 28

    Department

     

    Bioengineering Department

     

    Ingenieria Biomedica
  • ACCESS

    Student profile

    The program is addressed to graduates in the fields of science, health science and engineering. Specifically:

    • Holders of a UC3M master's degree in Management and Development of Biomedical Technologies or Clinical Engineering, both hosted by the same department of this Ph.D. program. 
    • Holders of a master's degree in biomedical engineering, clinical engineering or medical technologies engineering in general.
    • Holders of other master's degrees in engineering (industrial, electrical, electronic, computer, etc.) with an interest in biomedical research.
    • Holders of a master's degree in physics, mathematical, chemical or biological science, with an interest in applied biomedicine or bioengineering. 
    • Holders of a master's degree in biology, biotechnology, biochemistry, genetics, immunology, pharmacology, molecular biomedicine, regenerative biomedicina, molecular biomedicine and oncology, genetics and genomics engineering, or any other master's degree in the health sciences field in general, with an interest in advanced biomedical technology.
    • Students from other Ph.D. programs (either at UC3M or other Spanish or foreign universities) requesting a transfer to this program for considering it more suitable for their line of research. 

    Access requirements

    According to art. 6 of the PhD studies regulation (RD 99/2011), in order to access the Program it is required to have a Bachelor's degree (or equivalent) and a Master's degree (or equivalent), provided that at least 300 ECTS credits have been passed in these two cycles as a whole, or the equivalent degree qualifies for level 3 of MECES (Marco Español de Cualificaciones para la Educación Superior, Spanish Framework for Higher Education Qualifications).

    Likewise, access is available to candidates in possession of foreign degrees from countries integrated into the European Higher Education Area (EHEA) when the degree can be accredited as level 7 in the European Qualifications Framework (EQF), as long as the aforementioned degree allows access to PhD level studies in the country of expedition; and candidates with a degree which is equivalent to a Spanish Master's degree, obtained in foreign education systems outside the EHEA, as long as the aforementioned degree allows access to PhD level studies in the country of expedition.

    Admission criteria

     

    The selection and admission process follows the criteria established by the Academic Committee, as listed below. The Coordinator of the Committee will implement these and report to the Committee periodically. 

    Applicants must provide their bachelor's and master's degrees with academic transcripts, curriculum vitae, and a research project related to one or more of the lines of research of the program. 

    The Academic Committee will consider the following aspects:

    • English skills (minimum: B2)
    • Academic transcript (30%)
    • Suitability of academic background (subjects, grandes and language skills) for the lines of research of the program (30%)
    • Proof of research experience (publications, conferences, patents, etc.) (10%)
    • Motivation letter detailing the candidate's research interests and commitment to the program. Tha candidate can also provide recommendation letter(s) from researchers from any university or R&D center as additional proof of commitment (30%)
    • Endorsement letter for thesis project from a professor from the PhD program, indicating the project's connection to the lines of research of the program.

    The Academic Committee may request an interview with the candidate. This interview will not be considered part of the admission criteria but an additional element for assessment of the candidate's adequacy.

     

    Complementary training

    The Academic Committee can require up to 30 credits of complementary training in the field of biomedical engineering, mostly from subjects of the Master in Biomedical Technologies Management and Development Master in Clinical Engineering and further UC3M master's programs in bioengineering related to the line of research in which the candidate intends to develop their research project. These activities will not be considered as part of the Ph.D. program in any case.

     

    Seats available for the academic year: 10

     

     

  • FACULTY
  • TRAINING

    Specific training

     

    • Doctoral meetings

    Workshop-format sessions in which Ph.D. candidates present the status of their research before other PhD candidates, their tutors or advisors, and other professors of the program from the university. These meetings are conducted in English or Spanish.

    This training is mandatory: 20 hours per academic year (including 6 hours of in-person sessions).

    For assessment purposes, the Ph.D. candidate will provide proof of attendance and a report supervised by the thesis advisor detailing the conclusions and possible impact of the discussion on their research project. 

     

    • Conferences or presentations by the PhD candidate

    Presentations of variable duration before a qualified audience: congresses, meetings, masterclasses, etc. Students who cannot attend these forums can do these presentations in the context of the abovementioned doctoral meetings as an additional activity. These conferences or presentations are conducted in English or Spanish. 

    This training is mandatory: 7 hours per academic year (6 hours of preparation and 1 hour of presentation).

    For assessment purposes, the Ph.D. candidate will provide proof of attendance and a report supervised by the thesis advisor detailing the conclusions and possible impact of the discussion on their research project. 

     

    • Specific seminars

    Seminars, conferences or courses of variable duration hosted by this Ph.D. program or others from the Escuela Politécnica Superior, by departments, academic units, university institutes, health research institutes or hospitals from the Spanish healthcare system, or by other universities or research centers (national or regional). These seminars are conducted in English or Spanish. 

    This activity is not mandatory. However, the Academic Committee of the program may require 20 to 60 hours of this activity throughout the doctoral training, according to the training and former research or career experience of the Ph.D. candidate.

    For assessment purposes, the Ph.D. candidate will provide proof of attendance and a report supervised by the thesis advisor detailing the contents of the activity in relation to the subject of their research project. The Academic Committee has authority to validate or not the seminars hosted by institutions outside UC3M.

     

    • Specialized courses

    Short courses on the subjects listed below, with contents adapted to the different areas of the program. These courses are conducted in English and Spanish:

    • Tools and technology for biomedical research
    • Introduction to use of animals in research
    • Use of o de radiaciones ionizantes en investigación biomédica
    • Weekly seminars approved by the Committee of Continuing Education Activities of Comunidad de Madrid
    • Research seminars of IiSGM (Instituto de Investigación Sanitaria Gregorio Marañón)
    • Research seminars of CIEMAT
    • Monthly seminars on biomedical research updates at the Instituto de Investigaciones Sanitarias-FJD
    • Introduction of molecule imaging

    This activity is not mandatory. However, the Academic Committee of the program may require 20 to 60 hours of this activity throughout the doctoral training, according to the training and former research or career experience of the Ph.D. candidate.

    For assessment purposes, the Ph.D. candidate will provide proof of attendance and a report supervised by the thesis advisor detailing the contents of the activity in relation to the subject of their research project. The Academic Committee has authority to validate or not the seminars hosted by institutions outside UC3M.

     

    • Research visits in clinical centers, hospitals or research centers of national or foreign reference

    The program promotes the mobility of students with training activities and research visits in hospitals or research centers of reference either in Spain or abroad.

    These visits are recommended but not mandatory. The duration of the visit must be one month at least. They can be carried out throughout the doctoral training period, although they are recommended during the second or third year. Research visits at foreign centers qualify as a requirement for the Doctorado Internacional distinction. 

    Ph.D. candidates can attend courses and seminars organized by the host institution during the visit. This training can be considered as one of the requirements of the abovementioned activities (specific seminars, specialized courses, etc.).

    Once the visit has concluded, the Ph.D. candidate will provide a report detailing all activities, courses and seminars, as well as the progress on the thesis research made during the visit. This report has to be submitted to the Academic Comittee along with a certificate from the host company as proof of visit completion.

     

     

    Research skills training

     

    Research skills training is focused on abilities common to all disciplines for the development of scientific and educational skills and the improvement of the professional career.

    This activity is not mandatory. However, the Academic Committee of the program may require 20 to 60 hours of this activity throughout the doctoral training, according to the training and former research or career experience of the Ph.D. candidate.

    This training consists of different activities (short courses, seminars, etc.), which can be recommended by the Academic Committee of the program.

     

    Further information:

  • RESEARCH
    • Lines of research

      Biomedical Instrumentation and Imaging Group

      • Advances on X-ray imaging: Research on all the stages of image formation in X-ray systems, from the data acquisition to the image quantification, including calibration, image processing and tomographic reconstruction.
      • Technologies for Molecular Imaging: development of molecular imaging instrumentation (nuclear, magnetic resonance, etc.); analysis and quantitative processing of biomarkers in signals and images.
      • Molecular probes: synthesis of new imaging agents (radiotracers and nanoparticles) and their evaluation as specific molecular probes in biomedical applications.
      • Preclinical research: biomedical research lines, own or through external collaborations, using molecular imaging equipment (MRI, CT, PET, SPECT and optics). Main areas: Neuroimaging, Oncology, Cardiological Imaging, and Infection and Inflammation.
      • Technological development in optical imaging and biological applications: optical design, reconstruction and quantification methods for optical imaging systems, both for macroscopy and microscopy applications (optical fluorescence tomography, light sheet microscopy, confocal microscopy). Applications of light sheet microscopy and ultramicroscopy to obtain fast high-resolution images of three-dimensional specimens.
      • Image-guided Treatments: simulation, planning, guidance and evaluation of surgical interventions and therapeutic treatments with image component (TAC, US, RM ...) using different positioning systems and advanced processing algorithms.
      • Neuroimaging: development and clinical application of multimodal neuroimaging processing techniques by MRI, including structural imaging, spectroscopy, diffusion and functional for the study of normal and pathological brain.
      • Advanced biomedical image processing: advanced image processing techniques, including artificial intelligence, applied to microscopy, radiology or video images, oriented to segmentation, classification or quantification and with special focus on life sciences and clinically applicable solutions.

       

       

      Tissue Engineering and Regenerative Medicine

      • Search for biomarkers in rare skin diseases
      • Nanorobots in dermatology
      • Basic and preclinical research in advanced therapies: cell therapy and gene therapy. Bioengineering of tissues/organs and regeneration
      • Design and development by bioengineering of humanized animal models of dermatological diseases of high and low prevalence
      • Clinical research of advanced therapies
      • Role of physical forces in the formation, physiology and pathology of human tissues
      • Development of new techniques of micro- and nano-fabrication and microfluidics for the generation of cellular and tissue-scale structures: multi-organ-chip-technologies for the development of new drugs and lab-on-a-chip technologies for the analysis of cellular and tissue behavior
      • 3-D bioprinting of tissues and organs
      • Development of advanced and adaptable biomaterials for the modeling, diagnosis and treatment of diseases
    • Scientific results

      Thesis: Development of milk exosome-based probes for biomedical imaging. Mª Isabel González Gutiérrez. Defense: 28/11/2022.

      • Santos-Coquillat, A., Herreros-Pérez, D., Samaniego, R., González, M. I., Cussó, L., Desco, M., Salinas, B. Dual-labeled nanoparticles based on small extracellular vesicles for tumor detection. Biol Direct. 2022 Nov 14;17(1):31. doi: 10.1186/s13062-022-00345-7. PMID: 36376978; PMCID: PMC9664624. (2022)
      • Santos-Coquillat, A., González, M. I., Clemente-Moragón, A., González-Arjona, M., Albaladejo-García, V., Peinado, H., Muñoz, J., Ximénez Embún, P., Ibañez, B., Oliver, E., Desco, M., Salinas, B. Goat Milk Exosomes As Natural Nanoparticles for Detecting Inflammatory Processes By Optical Imaging. Small. 2022 Feb;18(6):e2105421. doi: 10.1002/smll.202105421. Epub 2021 Dec 2. PMID: 34854563. (2021)
      • Gómez-Cid, L., López-Donaire, M. L., Velasco, D., Marín, V., González, M. I., Salinas, B, Cussó, L., García, Á., Bravo, S. B., Fernández-Santos, M. E., Elvira, C., Sierra, J., Arroba, E., Bañares, R., Grigorian-Shamagian, L., Fernández-Avilés, F. Cardiac Extracellular Matrix Hydrogel Enriched with Polyethylene Glycol Presents Improved Gelation Time and Increased On-Target Site Retention of Extracellular Vesicles. Int J Mol Sci. 2021 Aug 26;22(17):9226. doi: 10.3390/ijms22179226. PMID: 34502146; PMCID: PMC8431142. (2021)
      • González, M. I., González-Arjona, M., Santos-Coquillat, A., Vaquero, J., Vázquez-Ogando, E., de Molina, A., Peinado, H., Desco, M., Salinas, B. Covalently Labeled Fluorescent Exosomes for In Vitro and In Vivo Applications. Biomedicines. 2021 Jan 16;9(1):81. doi: 10.3390/biomedicines9010081. PMID: 33467033; PMCID: PMC7829962. (2021)
      • González, M. I., Martín-Duque, P., Desco, M., Salinas, B. Radioactive Labeling of Milk-Derived Exosomes with 99mTc and In Vivo Tracking by SPECT Imaging. Nanomaterials (Basel). 2020 May 30;10(6):1062. doi: 10.3390/nano10061062. PMID: 32486215; PMCID: PMC7352469. (2020)

      Thesis: Percepción del emborronamiento estático y dinámico para el desarrollo de instrumentación clínica en optometría y oftalmología. Víctor Rodríguez López. Defense: 25/11/2022.

      • Rodríguez-Lopez, V., Dorronsoro, C. Beyond traditional subjective refraction. Current Opinion in Ophthalmology. 3(3), 228-234 (2022). DOI: 10.1097/ICU.0000000000000834. (2022)
      • Rodríguez-Lopez, V., Dorronsoro, C., Burge, J. Contact lenses, the reverse Pulfrich effect, and anti-Pulfrich monovision corrections. Scientific Reports, 10, 16086 (2020). DOI: https://doi.org/10.1038/s41598-020-71395-y. (2020)

      Thesis: Brain network alterations in Attention-Deficit and Hyperactivity Disorder: Towards an integrative perspective based on systems neuroscience. Luis Marcos Vidal. Defense: 28/10/2022.

      • Marcos-Vidal, L., Martínez-García, M., Martín de Blas, D., Navas-Sánchez, F, J., Pretus, C., Ramos-Quiroga, J. A., Richarte, V., Vilarroya, Ó., Sepulcre, J., Desco, M., Carmona, S. Local Functional Connectivity as a Parsimonious Explanation of the Main Frameworks for ADHD in Medication-Naïve Adults. J Atten Disord. 2022 Nov;26(13):1788-1801. doi: 10.1177/10870547221101646. Epub 2022 Jun 9. PMID: 35684934. (2022)
      • Pretus, C., Marcos-Vidal, L., Martínez-García, M., Picado, M., Ramos-Quiroga, J. A., Richarte, V., Castellanos, F. X., Sepulcre, J., Desco, M., Vilarroya, Ó., Carmona, S. Stepwise functional connectivity reveals altered sensory-multimodal integration in medication-naïve adults with attention deficit hyperactivity disorder. Hum Brain Mapp. 2019 Nov 1;40(16):4645-4656. doi: 10.1002/hbm.24727. Epub 2019 Jul 19. PMID: 31322305; PMCID: PMC6865796. (2019)
      • Marcos-Vidal, L., Martínez-García, M., Pretus, C., Garcia-Garcia, D., Martínez, K., Janssen, J., Vilarroya, O., Castellanos, F. X., Desco, M., Sepulcre, J., Carmona, S. Local functional connectivity suggests functional immaturity in children with attention-deficit/hyperactivity disorder. Hum Brain Mapp. 2018 Jun;39(6):2442-2454. doi: 10.1002/hbm.24013. Epub 2018 Feb 22. PMID: 29473262; PMCID: PMC6866394. (2018)

      Thesis: Prevención de la esquizofrenia: utilización de estrategias farmacológicas basadas en compuestos antiinflamatorios y antioxidantes en el modelo murino de estimulación inmunitaria materna. Luis Diego Romero Miguel. Defense: 16/09/2022.

      • Garcia-Partida, J. A., Torres-Sanchez, S., MacDowell, K., Fernández-Ponce, M. T., Casas, L., Mantell, C., Soto-Montenegro, M. L., Romero-Miguel, D., Lamanna-Rama, N., Leza, J. C., Desco, M., Berrocoso, E. The effects of mango leaf extract during adolescence and adulthood in a rat model of schizophrenia. Front Pharmacol. 2022 Jul 26;13:886514. doi: 10.3389/fphar.2022.886514. PMID: 35959428; PMCID: PMC9360613. (2022)
      • Casquero-Veiga, M., Lamanna-Rama, N., Romero-Miguel, D., Desco, M., Soto-Montenegro, M. L. In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats. J Vis Exp. 2022 Mar 23;(181). doi: 10.3791/63478. PMID: 35404344. (2022)
      • Lamanna-Rama, N., Romero-Miguel, D., Desco, M., Soto-Montenegro, M. L. An Update on the Exploratory Use of Curcumin in Neuropsychiatric Disorders. Antioxidants (Basel). 2022 Feb 10;11(2):353. doi: 10.3390/antiox11020353. PMID: 35204235; PMCID: PMC8868558. (2022)
      • Romero-Miguel, D., Casquero-Veiga, M., MacDowell, K. S., Torres-Sanchez, S., Garcia-Partida, J. A., Lamanna-Rama, N., Romero-Miranda, A., Berrocoso, E., Leza, J. C., Desco, M., Soto-Montenegro, M. L. A Characterization of the Effects of Minocycline Treatment During Adolescence on Structural, Metabolic, and Oxidative Stress Parameters in a Maternal Immune Stimulation Model of Neurodevelopmental Brain Disorders. Int J Neuropsychopharmacol. 2021 Sep 21;24(9):734-748. doi: 10.1093/ijnp/pyab036. PMID: 34165516; PMCID: PMC8453277. (2021)
      • Casquero-Veiga, M., Romero-Miguel, D., MacDowell, K. S., Torres-Sanchez, S., Garcia-Partida, J. A., Lamanna-Rama, N., Gómez-Rangel, V., Romero-Miranda, A., Berrocoso, E., Leza, J. C., Arango, C., Desco, M., Soto-Montenegro, M. L. Omega-3 fatty acids during adolescence prevent schizophrenia-related behavioural deficits: Neurophysiological evidences from the prenatal viral infection with PolyI:C. Eur Neuropsychopharmacol. 2021 May;46:14-27. doi: 10.1016/j.euroneuro.2021.02.001. Epub 2021 Mar 15. PMID: 33735708. (2021)
      • Casquero-Veiga, M., Bueno-Fernandez, C., Romero-Miguel, D., Lamanna-Rama, N., Nacher, J., Desco, M., Soto-Montenegro, M. L. Exploratory study of the long-term footprint of deep brain stimulation on brain metabolism and neuroplasticity in an animal model of obesity. Sci Rep. 2021 Mar 10;11(1):5580. doi: 10.1038/s41598-021-82987-7. PMID: 33692388; PMCID: PMC7946931. (2021)
      • Romero-Miguel, D., Lamanna-Rama, N., Casquero-Veiga, M., Gómez-Rangel, V., Desco, M., Soto-Montenegro, M. L. Minocycline in neurodegenerative and psychiatric diseases: An update. Eur J Neurol. 2021 Mar;28(3):1056-1081. doi: 10.1111/ene.14642. Epub 2020 Dec 24. PMID: 33180965. (2020)

      Thesis: Development, characterization and evaluation of advanced therapies for the treatment of cardiac pathologies. Lidia Gómez Cid. Defense: 23/05/2022.

      • Sánchez de la Nava, A. M., Gómez-Cid, L., Domínguez-Sobrino, A., Fernández-Avilés, F., Berenfeld, O., Atienza, F. Artificial intelligence analysis of the impact of fibrosis in arrhythmogenesis and drug response. Front Physiol. 2022 Oct 12;13:1025430. doi: 10.3389/fphys.2022.1025430. eCollection 2022.PMID: 36311248 (2022)
      • Sánchez de la Nava, A. M., Gómez-Cid, L., Ríos-Muñoz, G. R., Fernández-Santos, M. E., Fernández, A. I., Arenal, Á., Sanz-Ruiz, R., Grigorian-Shamagian, L., Atienza, F., Fernández-Avilés, F. Cardiovascular Diseases in the Digital Health Era: A Translational Approach from the Lab to the Clinic. BioTech (Basel). 2022 Jun 30;11(3):23. doi: 10.3390/biotech11030023. (2022)
      • Gómez-Cid, L., Grigorian-Shamagian, L., Sanz-Ruiz, R., de la Nava, A. S., Fernández, A. I., Fernández-Santos, M. E., Fernández-Avilés, F. The Essential Need for a Validated Potency Assay for Cell-Based Therapies in Cardiac Regenerative and Reparative Medicine. A Practical Approach to Test Development. Stem Cell Rev Rep. 2021 Dec;17(6):2235-2244. doi: 10.1007/s12015-021-10244-5. Epub 2021 Aug 31. (2021)
      • Gómez-Cid, L., López-Donaire, M.L., Velasco, D., Marín, V., González, M.I., Salinas, B., Cussó, L., García, Á., Bravo, S. B., Fernández-Santos, M.E., Elvira, C., Sierra, J., Arroba, E., Bañares, R., Grigorian-Shamagian, L., Fernández-Avilés, F. Cardiac Extracellular Matrix Hydrogel Enriched with Polyethylene Glycol Presents Improved Gelation Time and Increased On-Target Site Retention of Extracellular Vesicles. Int J Mol Sci. 2021 Aug 26;22(17):9226. doi: 10.3390/ijms22179226 (2021)
      • Del-Canto, I., Gómez-Cid, L., Hernández-Romero, I., Guillem, M. S., Fernández-Santos, M. E., Atienza, F., Such, L., Fernández-Avilés, F., Chorro, F. J., Climent, A. M. Front Physiol. 2Ranolazine-Mediated Attenuation of Mechanoelectric Feedback in Atrial Myocyte Monolayers. 2020 Aug 4;11:922. doi: 10.3389/fphys.2020.00922. eCollection 2020.PMID: 32848863 (2020)
      • Gómez-Cid, L., Moro-López, M., de la Nava, A. S., Hernández-Romero, I., Fernández, A. I., Suárez-Sancho, S., Atienza, F., Grigorian-Shamagian, L., Fernández-Avilés, F. Electrophysiological effects of extracellular vesicles secreted by cardiosphere-derived cells: unraveling the antiarrhythmic properties of cell therapies. Processes 2020; 8: 924. https://doi.org/10.3390/pr8080924. (2020)

      Thesis: Optimization of computer-assisted intraoperative guidance for complex oncological procedures. Mónica García Sevilla. Defense: 25/03/2022.

      • García-Sevilla, M., Moreta-Martinez, R., García-Mato, D., Arenas de Frutos, G., Ochandiano, S., Navarro-Cuéllar, C., Sanjuán de Moreta, G., and Pascau, J. Surgical Navigation, Augmented Reality, and 3D Printing for Hard Palate Adenoid Cystic Carcinoma En-Bloc Resection: Case Report and Literature Review. Front. Oncol, 11, 741191 (2022)
      • García-Sevilla, M., Mediavilla-Santos, L., Ruiz-Alba, M. T., Pérez-Mañanes, R., Calvo-Haro, J. A., and J. Pascau. Patient-specific desktop 3D-printed guides for pelvic tumour resection surgery: a precision study on cadavers. Int J CARS 16, 397–406 (2021)
      • García-Sevilla, M., Mediavilla-Santos, L., Moreta-Martinez, R., García-Mato, D., Pérez-Mañanes, R., Calvo-Haro, J. A., and Pascau, J. Combining Surgical Navigation and 3D Printing for Less Invasive Pelvic Tumor Resections. In IEEE Access (2021)
      • García-Sevilla, M., Moreta-Martinez, R., García-Mato, D., Pose-Diez-de-la-Lastra, A., Pérez-Mañanes, R., Calvo-Haro, J. A., and Pascau, J. Augmented Reality as a Tool to Guide PSI Placement in Pelvic Tumor Resections. Sensors, 21(23), 7824 (2021)
      • García-Sevilla, M., De León-Luis, J., Moreta-Martínez, R., García-Mato, D., Pérez-Mañanes, R., Calvo-Haro, J. A., and Pascau, J. Performance Evaluation to Improve Training in Forceps-Assisted Delivery. OR 2.0 Context-Aware Operating Theaters, Computer Assisted Robotic Endoscopy, Clinical Image-Based Procedures, and Skin Image Analysis, 11041, 69–77 (2018)

      Thesis: Identification and functional characterization of mutation-independent disease-severity modulators in recessive dystrophic epidermolysis bullosa. Esteban Gonzalo Chacón Solano. Defense: 18/03/2022.

      • Chacón-Solano, E.; León, C.; Carretero, M.; García, M.; Sánchez-Domínguez, R.; Quero, F.; Méndez-Jiménez, E.; Bonafont, J.; Ruiz-Mezcua, B.; Escámez, M.J.; Larcher, F.; Del Río, M. Mechanistic interrogation of mutation-independent disease modulators of RDEB identifies the small leucine-rich proteoglycan PRELP as a TGF-β antagonist and inhibitor of fibrosis. Matrix Biol. 2022 Aug;111:189-206. doi: 10.1016/j.matbio.2022.06.007. Epub 2022 Jun 30. PMID: 35779740 (2022)Chacón-Solano, E.; León, C.; Díaz, F.; García-García, F.; García, M.; Escámez, M.J.; Guerrero-Aspizua, S.; Conti, C.J.; Mencía, Á.; Martínez-Santamaría, L.; Llames, S.; Pévida, M.; Carbonell-Caballero J.; Puig-Butillé, J.A.; Maseda, R.; Puig, S.; de Lucas, R.; Baselga, E.; Larcher, F.; Dopazo, J.; Del Río, M. Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer-prone genodermatoses. Br J Dermatol. 2019 Sep;181(3):512-522. doi: 10.1111/bjd.17698. Epub 2019 Apr 15. PMID: 30693469; PMCID: PMC6850467 (2019)

      Thesis: Personalized medicine in surgical treatment combining tracking systems, augmented reality and 3D printing. Rafael Moreta Martínez. Defense: 17/12/2021.

      • Moreta-Martínez, R.; Rubio-Pérez, I.; García-Sevilla, M.; García-Elcano, L.; Pascau, J. Evaluation of optical tracking and augmented reality for needle navigation in sacral nerve stimulation. Comput Methods Programs Biomed. Sep;224:106991 (2022)
      • Moreta-Martinez, R.; Pose-Díez-de-la-Lastra, A.; Calvo-Haro, J. A.; Mediavilla-Santos, L.; Pérez-Mañanes, R.; and J. Pascau. Combining Augmented Reality and 3D Printing to Improve Surgical Workflows in Orthopedic Oncology: Smartphone Application and Clinical Evaluation. Sensors, 21(4), 1370 (2021)
      • Moreta-Martinez, R.; García-Mato, D.; García-Sevilla, M.; Pérez-Mañanes, R.; Calvo, J. A.; and J. Pascau. Combining Augmented Reality and 3D Printing to Display Patient Models on a Smartphone. J. Vis. Exp., 155, e60618 (2020)
      • Moreta-Martinez, R.; Calvo-Haro, J. A.; Pérez-Mañanes, R.; García-Sevilla, M.; Mediavilla-Santos, L.; and J. Pascau. Desktop 3D Printing: Key for Surgical Navigation in Acral Tumors? Appl. Sci., 10(24), 8984 (2020)
      • Moreta-Martinez, R.; García-Mato, D.; García-Sevilla, M.; Pérez-Mañanes, R.; Calvo, J. A.; and J. Pascau. Augmented reality in computer-assisted interventions based on patient-specific 3D printed reference. Healthcare Technology Letters, 1–5 (2018)

      Thesis: Methodology for the production of human hair follicles. Cristina Quílez López. Defense: 10/12/2021.

      • Quílez, C.; Cerdeira, E.; González-Rico, J.; De Aranda, G.; López, M. L.; Jorcano, J. L.;  Velasco, D. Evaluation of different methodologies for primary human dermal fibroblast spheroid formation: automation through 3D Bioprinting technology. Biomedical Materials (2022). DOI: 10.1088/1748-605X/ac7a7f. (2022)
      • Montero, A.; Quílez, C.; Valencia, L.; Girón, P.; Jorcano, J. L.; Velasco, D. Effect of fibrin concentration on the In Vitro production of Dermo-Epidermal equivalents. International Journal of Molecular Sciences, 22(13), 6746 (2021)
      • Quílez, C.; De Aranda, G.; García, M.; López, V.; Montero, A.; Valencia, L.; Velasco, D. Bioprinting for Skin. In: Crook J. (eds) 3D Bioprinting. Methods in Molecular Biology, vol 2140. Humana, New York, NY. ISBN: 978-1-0716-0520-2_14 (2020)
      • González-Rico, J.; Quílez, C.; Muñoz-Barrutia, A.; Jorcano, J. L.; Velasco, D. The role of hyaluronic acid and versican in the skin extracellular matrix. Biomecánica 27(1):35-49 (2020)
      • López-Iglesias, C.; Quílez, C.; Barros, J.; Velasco, D.; Alvarez-Lorenzo, C., Jorcano, J. L.; Monteiro, F. J.; García-González, C. A. Lidocaine-Loaded Solid Lipid Microparticles (SLMPs) Produced from Gas-Saturated Solutions for Wound Applications. Pharmaceutics 12(9):870 (2020)
      • Velasco, D.; Quílez, C.; García, M.; Del Cañizo, J. F.; Jorcano, J. L. 3D human skin bioprinting: a view from the bio side. Journal of 3D Printing in Medicine 2(3):141-162. FutureMedicine (2018)
      • Capítulo de libro: Stojic, M.; López, V.; Monteo, A.; Quílez, C.; De Aranda, G.; Vojtova, L.; Jorcano, J. L.; Velasco, D. Skin tissue engineering. Biomaterials for skin repair and regeneration. Woodhead Publishing - Skin tissue engineering, 59-99. ISBN 9780081025468 (2019)

      Thesis: Optimization of craniosynostosis surgery: virtual planning, intraoperative 3D photography and surgical navigation. David García Mato. Defense: 13/05/2021.

      • García-Mato, D.; Porras, A. R.; Ochandiano, s.; Rogers, g. f.; García-Leal, R.; Salmerón, J. I.; Pascau, J.; and Linguraru, M-G. Effectiveness of Automatic Planning of Fronto-orbital Advancement for the Surgical Correction of Metopic Craniosynostosis. Plastic and Reconstructive Surgery – Global Open 9(11), e3937 (2021)
      • García-Mato, D.; García-Sevilla, M.; Porras, A.R.; Ochandiano, S.; Darriba-Allés, J. V.; García-Leal, R.; Salmerón, J. I. ; Linguraru, M. G.; and J. Pascau. Three-Dimensional Photography for Intraoperative Morphometric Analysis in Metopic Craniosynostosis Surgery. Int J CARS 16, 277–287 (2021)
      • García-Mato, D.; Moreta-Martinez, R.; García-Sevilla, M.; Ochandiano, S.; García-Leal, R.; Pérez-Mañanes, R.; Calvo-Haro, J. A.; Salmerón, J. I.; and Pascau, J. Augmented reality visualization for craniosynostosis surgery. Comput. Methods Biomech. Biomed. Eng. Imaging Vis., 1–8 (2020)
      • García-Mato, D.; Ochandiano, S.; García-Sevilla, M.; Navarro-Cuéllar, C.; Darriba-Allés, J.V.; García-Leal, R; Calvo-Haro, J.A.; Pérez-Mañanes, R.; Salmerón, J. I.; and Pascau, J. Craniosynostosis surgery: workflow based on virtual surgical planning, intraoperative navigation and 3D printed patient-specific guides and templates. Scientific Reports, 9, 17691 (2019)

      Thesis: Gene editing-based Protocols for the ex vivo correction of recessive dystrophic epidermolysis bullosa. José Bonafont Aragó. Defense: 28/09/2020.

      • Bonafont, J., Mencía, A., Chacón-Solano, E., Srifa, W., Vaidyanathan, S., Romano, R., García, M., Hervás-Salcedo, R., Ugalde, L., Duarte, B., Porteus, M.H., Del Rio, M., Larcher, F., Murillas, R. Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing. Mol Ther. 2021 Jun 2;29(6):2008-2018. doi: 10.1016/j.ymthe.2021.02.019. Epub 2021 Feb 18. PMID: 33609734; PMCID: PMC8178438. (2021)
      • Bonafont, J., Mencía, Á., García, M., Torres, R., Rodríguez, S., Carretero, M., Chacón-Solano, E., Modamio-Høybjør, S., Marinas, L., León, C., Escámez, M.J., Hausser, I., Del Río, M., Murillas, R., Larcher, F. Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing. Mol Ther. 2019 May 8;27(5):986-998. doi: 10.1016/j.ymthe.2019.03.007. Epub 2019 Mar 15. PMID: 30930113; PMCID: PMC6520462. (2019)
      • Patente: Gene Editing for the treatment of epidermolysis bullosa. Bonafont, Aragó, José; Larcher Laguzzi, Fernando; Murillas Angoiti, Rodolfo; Del Río Nechaevsky, Marcela; Mencía Rodríguez, Ángeles; García Díez, Marta; Escámez Toledano, María José; Porteus, Matthe. WO/2021/148483. PCT/EP2021/051224. 

       

    • Scientific publications

      This is a sample of relevant faculty publications:

      • Gordaliza, P. M., Muñoz-Barrutia, A., Via, L. E., Sharpe, S., Desco, M., & Vaquero, J. J. Computed Tomography-Based Biomarker for Longitudinal Assessment of Disease Burden in Pulmonary Tuberculosis. Molecular Imaging and Biology, 1-6, 2018. Q1.
      • M. Abella, C. de Molina, N. Ballesteros, A. García-Santos, A. Martínez, I. García, M. Desco. Enabling tomography with low-cost C-arm systems, Plos One 13(9): e0203817, 2018. Q1.
      • Hoekzema, E., Barba-Müller, E., Pozzobon, C., Picado, M., Lucco, F., García-García, D., Soliva J.C., Tobeña, A., Desco, M., Crone, E.A., Ballesteros, A., Carmona, S., Vilarroya, O. ‘Pregnancy leads to long-lasting changes in human brain structure’. Nature Neuroscience, 20(2):287-296 (2017)
      • Gómez-Gaviro, M.V., Balaban, E., Bocancea, D., Lorrio, M.T., Pompeiano, M., Desco, M., Ripoll, J., and Vaquero, J.J. ‘Optimized CUBIC protocol for three-dimensional imaging of chicken embryos at single-cell resolution’. Development, 144, (11), pp. 2092-2097 (2017)
      • Parellada, M., Pina-Camacho, L., Moreno, C., Alemán, Y., Krebs, M.O., Desco, M., Merchán-Naranjo, J., Del Rey-Mejías, A., Boada, L., Llorente, C., Moreno, D., Arango, C., Janssen, J. ‘Insular pathology in young people with high-functioning autism and first-episode psychosis’. Psychol Med, 47(14): 2472-2482 (2017)
      • Martínez, K., Janssen, J., Pineda-Pardo, J.A., Carmona, S., Román, F.J., Alemán-Gómez, Y., García-García, D., Escorial, S., Quiroga, M.A., Santarnecchi, E., Navas-Sánchez, F.J., Desco, M., Arango, C., Colom, R. ‘Individual differences in the dominance of interhemispheric connections predict cognitive ability beyond sex and brain size’. Neuroimage, 155: 234-244 (2017)
      • Abella, M., Serrano, E., Garcia-Blas, J., García, I., de Molina, C., Carretero, J., Desco, M. ‘FUX-Sim: An implementation of a fast universal simulation/reconstruction framework for X-ray systems’. Plos One, 12(7): e0180363 (2017)
      • Herraiz, J.L., Herranz, E., Cal-González, J., Vaquero, J.J., Desco, M., Cussó, L., and Udías, J.M. ‘Automatic Cardiac Self-Gating of Small-Animal PET Data’. Mol Imaging Biol, 18, (1), pp. 109-116 (2016)
      • Abascal, F.P.J., Abella, M., Marinetto, E., Pascau, J., Desco, M. ‘A novel prior- and motion-based compressed sensing method for small-animal respiratory gated CT’. PLoS One 11(3), e0149841 (2016)
      • Cubo, N., Garcia, M., Del Cañizo, J.F., Velasco, D., Jorcano, J.L. ‘3D bioprinting of functional human skin: production and in vivo analysis’. Biofabrication, 5;9(1):015006. PMID: 27917823 (2016)
      • Carretero, M., Guerrero-Aspizua, S., Illera, N., Gálvez, V., Navarro, M., García-García, F., Dopazo, J., Jorcano, J.L., Larcher, F., del Rio, M. ‘Differential Features between Chronic Skin Inflammatory Diseases Revealed in Skin-Humanized Psoriasis and Atopic Dermatitis Mouse Models’. J Invest Dermatol; 136(1):136-45. doi: 10.1038/JID.2015.362. PMID: 26763433 (2016)
      • García, M., Quintana-Bustamante, O., Segovia, J.C., Bueren, J., Martínez-Santamaría, L., Guerrero-Aspizua, S., Escámez, M.J., Del Rio, M., Larcher, F. ‘Long-term skin regeneration in xenografts from iPSC teratoma-derived human keratinocytes’. Exp Dermatol. 2016 Sep;25(9):736-8. doi: 10.1111/exd.13049. Epub 2016 Jun 30. PMID: 27095005 (2016)
      • Mencía, Á., García, M., García, E., Llames, S., Charlesworth, A., de Lucas, R., Vicente, A., Trujillo-Tiebas, M.J., Coto, P., Costa, M., Vera, Á., López-Pestaña, A., Murillas, R., Meneguzzi, G., Jorcano, J.L., Conti, C.J., Escámez Toledano, M.J., del Río Nechaevsky, M. ‘Identification of two rare and novel large deletions in ITGB4 gene causing epidermolysis bullosa with pyloric atresia’. Exp Dermatol. 2016 Apr;25(4):269-74. doi: 10.1111/exd.12938. Epub 2016 Feb 13. PMID: 26739954 (2016)
      • Navas-Sánchez, F.J., Carmona, S., Alemán-Gómez, Y., Sánchez-González, J., Guzmán-de-Villoria, J., Franco, C., Robles, O., Arango, C., and Desco, M. ‘Cortical morphometry in frontoparietal and default mode networks in math-gifted adolescents’. Hum Brain Mapp, 2016, 37, (5), pp. 1893-1902 (2016)
      • Vaquero, J.J.; Kinahan, P. ‘Positron Emission Tomography: Current Challenges and Opportunities for Technological Advances in Clinical and Preclinical Imaging Systems’. Annual Review of Biomedical Engineering, 17, 385:414, 10.1146/annurev-bioeng-071114-040723 (2015)
      • Carmona, S., Hoekzema, E., Castellanos, F.X., García-García, D., Lage-Castellanos, A., Van Dijk, K.R.A., Navas-Sánchez, F.J., Martínez, K., Desco, M., Sepulcre, J. ‘Sensation-to-cognition cortical streams in attention-deficit/hyperactivity disorder’. Hum Brain Mapp, 36(7): 2544-2557 (2015)
      • Arranz, A., and Ripoll, J. ‘Advances in optical imaging for pharmacological studies’. Front Pharmacol, 6, pp. 189 (187 pp) (2015)
      • Solé, C.V., Calvo, F.A., Polo, A., Cambeiro, M., González, C., Desco, M., and Martínez-Monge, M. ‘Intraoperative Electron-Beam Radiation Therapy for Pediatric Ewing Sarcomas and Rhabdomyosarcomas: Long-Term Outcomes’. Int J Radiat Oncol, 92, (5), pp. 1069-1076 (2015)
      • Martín-Mateos, P., Crespo-Garcia, S., Ruiz-Llata, M., Lopez-Fernandez, J.R., Jorcano, J.L., Del Rio, M., Larcher, F., Acedo, P. ‘Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation’. Biomed Opt Express; 5(9):3231-7. doi: 10.1364/BOE.5.003231. PMID: 25401034 (2014)
      • Montesinos, P., Abascal, J.F.P.J., Cussó, L., Vaquero, J.J., Desco, M. ‘Application of the Compressed Sensing Technique to Self-Gated Cardiac Cine Sequences in Small Animals’. Magn Reson Med, 72(2): 369-380 (2014)
      • Fernández-de-Manuel, L., Wollny, G., Kybic, J., Jiménez-Carretero, D., Tellado, J.M., Ramón, E., Desco, M., Santos, A., Pascau, J., Ledesma-Carbayo, M.J. ‘Organ-focused mutual information for nonrigid multimodal registration of liver CT and Gd-EOB-DTPA-enhanced MRI’. Med Image Anal, 18(1): 22-35 (2014)
      • Cussó, L., Vaquero, J.J., Bacharach, S., Desco, M. ‘Comparison of Methods to Reduce Myocardial 18F-FDG Uptake in Mice: Calcium Channel Blockers versus High-Fat Diets’. PLoS One, 9(9): e107999 (6pp) (2014)
      • Kiritsi, D., Garcia, M., Brander, R., Has, C., Meijer, R., Escámez, M.J., Kohlhase, J., van den Akker, P.C., Scheffer, H., Jonkman, M.F., del Rio, M., Bruckner-Tuderman, L., Pasmooij, A.M. ‘Mechanisms of natural gene therapy in dystrophic epidermolysis bullosa’. J Invest Dermatol; 134(8):2097-104. doi: 10.1038/jid.2014.118. Epub 2014 Feb 27. PMID: 24577406 (2014)
      • Zapatero-Solana, E., García-Giménez, J.L., Guerrero-Aspizua, S., García, M., Toll, A., Baselga, E., Durán-Moreno, M., Markovic, J., García-Verdugo, J.M., Conti, C.J., Has, C., Larcher, F., Pallardó, F.V., Del Rio, M. ‘Oxidative stress and mitochondrial dysfunction in Kindler syndrome’. Orphanet J Rare Dis; 9:211. doi: 10.1186/s13023-014-0211-8. PMID: 25528446 (2014)
      • Puig-Butille, J.A., Escámez, M.J., Garcia-Garcia, F., Tell-Marti, G., Fabra, À., Martínez-Santamaría, L., Badenas, C., Aguilera, P., Pevida, M., Dopazo, J., del Río, M., Puig, S. ‘Capturing the biological impact of CDKN2A and MC1R genes as an early predisposing event in melanoma and non melanoma skin cancer’. Oncotarget.; 5(6):1439-51.  PMID: 24742402 (2014)
      • Chamorro C., Almarza, D., Duarte, B., Llames, S.G., Murillas, R., García, M., Cigudosa, J.C., Espinosa-Hevia, L., Escámez, M.J., Mencía, A., Meana, A., García-Escudero, R., Moro, R., Conti, C.J., Del Río, M., Larcher, F. ‘Keratinocyte cell lines derived from severe generalized recessive epidermolysis bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo’. Exp Dermatol;22(9):601-3. doi: 10.1111/exd.12203. PMID: 23947675 (2013)
      • Martínez-Santamaría, L., Conti, C.J., Llames, S., García, E., Retamosa, L., Holguín, A., Illera, N., Duarte, B., Camblor, L., Llaneza, J.M., Jorcano, J.L., Larcher, F., Meana, Á., Escámez, M.J., Del Río, M. ‘The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model’. Exp Dermatol; 22(3):195-201. doi: 10.1111/exd.12097 (2013)
  • THESIS

    Thesis defense

     

    The doctoral thesis consists of an original research work developed by the doctoral student in the field of knowledge established by the program, which enables the student for autonomous work in the field of R+D+i.

    Universidad Carlos III de Madrid and its Doctoral School establish follow-up procedures to guarantee the quality of the student's training and supervision. They also facilitate the procedures for the proper evaluation and defense of the doctoral thesis.

     

    Further information:

     

     

     

    Requirements for thesis defense

    The Ph.D. candidate must have at least two publications as first author in indexed journals (Q2 or higher), or one publication as first author plus two contributions to an international congress, all of which must be derived from thesis work.

    A national, international or PCT patent can also be considered as equivalent to a publication or a congress communication. 

  • USEFUL INFORMATION
    • Ph.D. Studies Overview
      Información Práctica de los Estudios de Doctorado

       

      Our Ph.D. programs focus on the acquisition of skills and abilities required to undertake high-quality research work within the strategic framework and lines of research of the university. Students will be expected to work independently under supervision and guidance of top experts in their fields in order to produce novel, groundbreaking research work in the form of a dissertation.

      The Ph.D. thesis constitutes the expected outcome of the doctoral training, stating the specifics of the research work and results. The thesis must meet the high-quality standards required by the Ph.D. program and be subject to public defense and assessment by an independent thesis committee.

      A favorable assessment of the thesis enables Ph.D. students to request their official Ph.D. degree certificate, issued by the Spanish Ministerio de Educación, Cultura y Deporte.

       

      Doctoral training calendar 

      Duration of the academic year: October 1st through September 30th

      Process Period
      Admission According to the start semester of the PhD:

      Second semester of the 23/24 academic year
      Admission application deadline: September 1st 2023 through January 31st 2024 (23:59 h., CET) 
      PhD start date: March 30th 2024

      First semester of the 24/25 academic year
      Admission application deadline: February 1st through August 31st 2024 (23:59 h., CET) 
      PhD start date: November 15th 2024
      Enrollment According to the start semester of the PhD:

      Enrollment period for new students
      First semester: July 24th through 30th and September 1st through 30th (23:59 h., CET) of the current academic year
      Second semester: March 1st through 30th (23:59 h., CET) of the current academic year

      Enrollment period for continuing students
      September 1st through 30th (23:59 h., CET) of the current academic year
      Annual Assessment  June
      All PhD candidates are subject to annual evaluation.

      December
      Only students whose June evaluation was unfavorable are subject to evaluation. 

      In both cases the evaluation is based on the progress of the thesis project (Reseach Plan) and the doctoral activities carried out during the academic year.
       
      Thesis Defense Thesis defense can be carried out throughout the academic year.
       
    • Procedures
    • FAQ

      Ph.D. Studies

      Parque de las Moreras

      What is a Ph.D.?

      A Ph.D. is a period of training in skills and abilities required to undertake independent, high-quality research work in the realm of R&D under the supervision of top experts in their respective fields.

      What are the terms of access to a Ph.D. program?

      As a general rule, candidates are required to hold a Bachelor’s and a Master’s degree. Credits for both must amount to at least 300 ECTS credits.

      Additionally, specific requirements and candidate profiles are described in each program’s terms of access. Before applying for admission, it is strongly recommended to take the  Ph.D. Programs into consideration, as well as its lines of research, profiles of the scholars involved and final results (theses and scientific publications) as proof of the program’s quality and specialization.

      Shat is the duration of a Ph.D.?

      The regular duration of a full-time Ph.D. program is 4 years. This period can be extended up to 5 years.

      The regular duration of a part-time Ph.D. program is 7 years. This period can be extended up to 8 years. 

      You may apply, for justified reasons, for either an extension or a leave of absence from your Ph.D. training period to the Academic Committee of your program. Your request must be endorsed by your tutor/advisor. Further information:  Duration of Ph.D. studies

      Can I do my Ph.D. entirely online?

      No. All Ph.D. Programs require some face-to-face activity throughout the training period. The duration of face-to-face activity is established by each Program.

      How can I apply for a part-time enrollment status?

      You can state your part-time enrollment status upon admission or, once you have initiated your training period, by submitting a request for justified reasons to the Academic Committee of your program. Your request must be endorsed by your tutor/advisor. Further information:  Enrollment status for Ph.D. studies

      If you are the recipient of a pre-doctoral contract with the UC3M, you must be a full-time student for the entire duration of the contract in application of article 21 of Law 14/2011, of  the1st of June, on Science, Technology and Innovation.

      Must I take any other training in addition to my research work?

      Yes. There are three different types of additional training to be taken during your Ph.D.:

      • Complementary training. Applicable only to students whose terms of admission state this training as required.
      • Specific training. Activities within the framework of your Ph.D. program.
      • Research Skills training. Courses or activities focused on abilities common to all disciplines (communication, academic writing, stress management, etc.).

      Further information on Doctoral Training: Monitoring and Development of these FAQ.

      A favorable assessment enables students to apply for their official Ph.D. degree certificate issued by the Spanish Ministerio de Educación, Cultura y Deporte. An additional Doctorado Internacional distinction is awarded to students who met a number of specific requirements during their training period.


      What is an Interuniversity Ph.D.?

      Interuniversity PhDs are joint degree programs by Universidad Carlos III de Madrid in collaboration with other Spanish or international institutions. The outcome of these programs does not translate into multiple degrees but just one equivalent to the training undertaken by the student.

      Admission

      How can I apply for admission to a Ph.D. program?

      Your application for admission must be submitted online. Signing in is previously required in order to get your login and password. Further information on how to carry out this process:  Apply for admission

      I have not completed my Master’s degree yet. May I apply for admission now?

      According to art. 6 of the PhD studies regulation (RD 99/2011), in order to access the PhD studies it is required to have a Bachelor's degree (or equivalent) and a Master's degree (or equivalent), provided that at least 300 ECTS credits have been passed in these two cycles as a whole, or the equivalent degree qualifies for level 3 of MECES (Marco Español de Cualificaciones para la Educación Superior, Spanish Framework for Higher Education Qualifications).

      Likewise, access is available to candidates in possession of foreign degrees from countries integrated into the European Higher Education Area (EHEA) when the degree can be accredited as level 7 in the European Qualifications Framework (EQF), as long as the aforementioned degree allows access to PhD level studies in the country of expedition; and candidates with a degree which is equivalent to a Spanish Master's degree, obtained in foreign education systems outside the EHEA, as long as the aforementioned degree allows access to PhD level studies in the country of expedition.

      When can I apply for admission?

      Applications for admission for the first semester of the 24/25 academic year with start date on the 15th of November 2024 can be submitted from February 1st through August 31st 2024 (Spanish peninsular time, CET)*

      Applications for admission for the second semester of the 24/25 academic year with start date on the 30th of March 2025 can be submitted from September 1st 2024 through January 31st 2025 (Spanish peninsular time, CET)*.

      *Except where noted in the details of each Ph.D. Program.

      The PhD academic year begins on October 1st and ends on September 30th. 

      What documents do I need to submit?

      Scan in advance, in pdf format, the documentation requirements to be attached to your application. The documents listed below are mandatory in all cases:

      • National Identity Document: DNI, NIE, or passport
      • Previous degree certificate or diploma (Master’s degree or equivalent), or proof of payment of issuance fees. 
      • Academic transcript of previous degree (Bachelor's and Master’s degree or equivalent), including grades
      • Curriculum Vitae
      • Authorization of disclosure of educational and employment information
      • Ph.D. research proposal
      • Endorsement for thesis project

      Some programs may require additional documents, such as reference letters by notable researchers, foreign language skills certificate, etc.

      Can I choose when to start my doctoral training?

      Yes. As a new student, you must state in your application for admission whether you want to start your training in the first semester (November 15) or second semester (March 30).

      I want to apply for a scholarship or financial aid program. Must I do it before or after applying for admission to a Ph.D.?

      It is strongly recommended to apply first for your Ph.D. program of choice at uc3m, as most of the granting institutions require proof of admission (or application for admission) to a Ph.D.

      Further information on Scholarships and Financial Aid Programs of these FAQ.

      I submitted my application. When will I know if I am admitted?

      The review process of your application consists of two stages:

      • Administrative validation. Your application will be reviewed at the Doctoral School Office on campus to ensure that it meets the admission requirements. You will be contacted if necessary.
      • Academic evaluation. If your application has succesfully passed the previous stage, it will be forwarded to the Academic Committee of the Ph.D. program for review. You will be notified of the Committee's decision by certified mail sent to the postal address provided in your application.

      This process may take up to one-two months. You will be notified of the Committee’s resolution by e-mail.

      I have been admitted. When must I submit my enrollment form?

      In you are admitted to a Ph.D. program, you have to submit your online application for enrollment in the periods set by the university to that effect, according to the instructions indicated in your letter of admission, our website or the Enrollment section of this FAQ, including the payment of tuition fees. If you do not submit your enrollment for the academic year for which you were admitted, your admission will be cancelled.

      Doctoral training scholarships. Exemptions

      Campus Getafe

      What types of financial aid programs can I apply for?

      There is a wide variety of financial aid programs for doctoral training that cover partial or total tuition fees and, in some cases, allow uc3m to formally hire the Ph.D. student as a training researcher.

      Who are the awarding bodies?

      Here is a list of the most common scholarship and financial aid programs:

         - Formación de Investigadores del Ministerio de Innovación / Researchers Training by Ministerio de Innovación (formerly known as FPI scholarships)
         - Formación de Profesorado Universitario del Ministerio de Educación / University Faculty Training by Ministerio de Educación (formerly known as FPU scholarships)
         - Researchers Training by Universidad Carlos III de Madrid, awarded by the institution departments
         - Ph.D. Scholarships by La Caixa
         - Ph.D. Scholarships by Comunidades Autónomas (Autonomous Regions of Spain)
         - Scholarships by Fundación Carolina (for Latin American students)
         

      Further information:  Doctoral Training Scholarships


      When and how can I apply for these?

      Each granting body has its own application and awarding periods. It is strongly recommended to apply first for your Ph.D. program of choice at uc3m in all cases, as most of these institutions require proof of admission (or application for admission) to a Ph.D.

       

      Do I have to be admitted to a Ph.D. in order to apply for admission?

      It is not required in most cases, but, as pointed out previously, you must have at least submitted your application for admission in order to be eligible (check the awarding institution’s specific terms). Only if you are eventually granted the scholarship or financial aid will it be required to be admitted and enrolled on the program in order to accept the aid and be hired as a training researcher at uc3m.

       

      I received a scholarship or financial aid. Do I have to notify uc3m?

      Yes. As a recipient of any financial aids, it is recommended to notify the university for these to be applied upon enrollment. If your scholarship status is not registered in your self-enrollment application, please contact the Doctoral School Office, either in person or by e-mail at admisiondoctorado@uc3m.es

       

      Where will I undertake my Ph.D. research work?

      Your research and teaching activities (when applicable) will be carried out at the department or Institute stated in your contract within the framework of your Ph.D. program under the supervision of the tutor and advisor(s) appointed by the Academic Committee.


      Who is in charge of managing my scholarship or financial aid program?

      Granting institutions usually delegate on uc3m the management of these aids according to the terms originally established by those and our own rules and regulations.

       

      Who is to evaluate the progress and outcomes of my research work?

      All our Ph.D. students must submit the progress of their research work for evaluation by the Academic Committee of their Ph.D. program. Recipients of any financial aid program must also provide this information to the granting body.

       

      Are there any other tuition fees exemptions?

      Yes. As a new student, if you are eligible for any of the following exemptions or discounts recognized by the Spanish administration, you must submit certified copies of the pertinent documents to the Postgraduate Office on campus before enrollment proceedings so that these exemptions apply upon enrollment.

      • Large Family status: Certified copy of the Large Family status card (general or special)
      • Disability: Certified copy of Disability Identification card (minimum 33% disability)
      • Other: Certified copy of proof of exemption for victims of terrorist attacks (including their spouses and children) or children of civil and military servants who perished in the line of duty.

      These documents must be valid for the academic year for which the exemption is requested.

      Enrollment

      How to enroll

      Our Ph.D. Management platform allows to process your enrollment online. To access the platform, enter your UC3M username and password.

      When to enroll               

      New students can choose the start date of the Ph.D. studies. Enrollment period varies accordingly:

      Students starting first semester:

      • Enrollment period: July 24 through 30 and September 1st through 30th (23:59 h., Peninsular Spanish time)
      • Start date of Ph.D. training: November 15 

      Students starting second semester*:

      • Enrollment period: March 1st through 30th (23:59 h., Peninsular Spanish time)
      • Start date of Ph.D. training: March 30

      *In these cases, students benefit from a reduced tuition fee, applicable only for first-year enrollment.

      Your start date will determine the length of your Ph.D. training period.

      As a continuing student, the enrollment period is September 1st through 30th (23:59 h., Peninsular Spanish time) of each academic year.

      What modules should I register on my application?

      You must select the following modules of your enrollment application:

      • Ph.D. Monitoring for your doctoral training year. 

      Required in all cases. It will be registered by default in your application. 

      • Complementary credits.

      Only applicable if the Academic Committee of your program established these credits as obligatory in its admission resolution, in which case you have been properly notified in your admission letter. These credits will be registered by default in your application.

      Other activities of your doctoral training may not require enrollment. If so, our Doctoral School Office is in charge of the registration process:

      • Specific training: Activities included in the curriculum of your Ph.D. program. 
      • Research Skills training: Only required for students of some Ph.D. programs.  

      What are the costs of tuition fees?

      These are the tuition fees for all your Ph.D. training:

      1. Academic fees

      Academic monitoring of Ph.D. training year.  

      • Ordinary fee (full-time, starting first semester): 390 €.
      • Reduced fee* (full-time, starting second semester): 234 €.
      • Reduced fee (part-time, starting first or second semester): 234 €.

                  *Full fees will apply in subsequent years.

      Training credits

      • Complementary training (only for students who are required to take these credits as established in their resolution of admission). If the subjects are the same as subjects from an official degree, the price will be the same as in the original degree. The prices range from € 45,02 to € 80-150 €, depending on the master's program and the doctoral year of enrollment (first, second or subsequent).
      • Research Skills training courses. 45,02 € per credit. Credits from other institutions also require an enrollment at UC3M . A reduced 25% fee will apply in these cases (11,25 € per credit).

      Thesis defense. 143,15 €

      Ph.D. Degree Certificate. 229,86 €

      1. Administrative fees
      • Registrar’s Office expenses. 6,11 €
      • Academic record proceedings (first-year students only). 27,54 €
      1. School insurance. 1, 12 €. Applicable to Spanish or international students (legal residents) under 28 years of age.

      Students who fail to fulfill the payment of these fees will be dismissed from the Ph.D. program.

      Further information:  Tuition fees

      How do I validate my first-year enrollment?

      Upon completion and payment of your enrollment, the Doctoral School will get in touch with you and set an appointment to provide the original documents to have your enrollment validated in compliance with the access requirements to Ph.D.

      Documents

      According to your previous studies, the documents to be submitted are listed below: 

      1. If you have taken an official Master's degree at UC3M, you are not required to submit any documents. The Doctoral School will check your records accordingly.

      2. If your access degree for Ph.D. was issued by a University from Spain or a European Union country, or a state of the European Economic Area or Switzerland, it is required to provide the following original documents: 

      • Access degree certificate for Ph.D. (Master's degree or equivalent) or payment receipt of issuance fees.
      • Grades certificate of access degree to Ph.D. (Master's degree or equivalent).

      3. If your access degree for Ph.D. was issued by a University from a country other than the ones indicated above, it is required to provide the following legalized documents:

      • Access degree certificate for Ph.D. (Master's degree or equivalent) or payment receipt of issuance fees.
      • Grades certificate of access degree to Ph.D. (Master's degree or equivalent).

      There are different ways to have your documents legalized. Find which legalization procedure applies in your case:  Legalization of Foreign Degrees

      Please note that the legalization procedure must be carried out from the home country. It is strongly recommended to do it in advance. 

      Original hard copies of the documents must be provided along with their photocopies. The Doctoral School will check both originals and their copies and have them certified. If the degree certificates and documents have an electronic signature or digital certification (with safe verification codes), these will be submitted by e-mail at admisiondoctorado@uc3m.es.

      All documents must be submitted in Spanish, English, French, Italian or Portuguese (certificates and degrees provided in other languages must have attached an official Spanish translation).  

      The submission period will be notified by e-mail within a month after the end of the enrollment period.

      What are my rights and obligations as a uc3m student?

      Please refer to the following documentation issued by the regional authorities and uc3m. All of them apply to Ph.D. candidates at Uc3m.

      • Students Statute of the Region of Madrid (Estatuto del estudiante de la Comunidad de Madrid)
      • uc3m students Rights and Obligations (Carta de los derechos y deberes del estudiante en la uc3m)
      • Rules and Regulations of the Doctoral School at uc3m (Reglamento de la Escuela de Doctorado de la uc3m)
      • Good Practices of the Doctoral School at uc3m (Código de buenas prácticas de la Escuela de Doctorado de la uc3m)

      Additionally, you have access to the university's support services to students and researchers.

      Further information:  Rules and Regulations

      Ph.D. Studies: Monitoring and Development

      Biblioteca María Moliner

      How are my Ph.D. supervisors appointed?

      Ph.D. tutors and advisors are advanced members of the uc3m faculty or other research institutions who serve as mentors of your research work and keep track of your progress. They also facilitate your communication with the Academic Committee of the program.

      Tutors are appointed by the Committee upon your admission. Tutors must hold a Ph.D. degree and have ties with the program, as well as a proven track record in research of at least six years (or proof of equivalent qualifications).

      The Committee will also appoint an advisor within three months from initial enrollment on the program. Thesis advisors must hold a Ph.D. degree and have a proven track record in research of at least six years (or equivalent qualifications), as well as specific research experience in the field of your thesis. Advisors' may be based at any university, center or institute in Spain or abroad. A professor may be appointed as both tutor and advisor of a Ph.D. student.

      The Academic Committee may change these designations throughout your doctoral training period for justified reasons.

      Must I take any other training in addition to my research work?

      Yes. There are three different types of additional training to be taken during your Ph.D.:

      • Complementary training. Maximum: 40 ECTS credits. Applicable only to students whose terms of admission state this training as required. The Academic Committee will determine the credit-based courses or subjects in the admission resolution. As a general rule, this training must be taken during the first year.
      • Specific training. Students are also expected to participate in a number of activities relevant to their field of research: seminars, meetings, conferences, courses, etc. These activities may require prior enrollment at uc3m. Your tutor or advisor will confirm the contents of your specific training program.
      • Research Skills training. Some Ph.D. programs at uc3m require training in research skills focused on abilities common to all disciplines (communication, academic writing, stress management, etc.). These credits can be earned at either uc3m or other institutions and require formal enrollment at uc3m in all cases, as well as the approval of your tutor or advisor.

      How is the progress of my research evaluated?

      The Academic Committee of your program will evaluate the progress of your research project and activity report on an annual basis in the month of June. Grounds for evaluation are to be registered in the following documents:

      • Research Plan. Not to be mistaken for the research proposal submitted when applying for admission. As a new Ph.D. student, you must elaborate an initial Research Plan within the first year of your doctoral training period. This plan will serve as a tracking tool of your project, listing the objectives and methodology of your research as well as a comprehensible timeline stating the periods estimated for the achievement of each goal. It must have attached your tutor or advisor's evaluation report in order to be submitted for assessment to the Academic Committee of your program.

      An annual update of this Plan must be submitted in subsequent years, with the corresponding tutor or advisor’s evaluation report, so that all parties involved in your doctoral training can track and assess your progress.

      • Activity Report. In addition to your Research Plan (initial or updated), it is also required to register any activity relevant to your Ph.D. research: courses, seminars, meetings, conventions, publications, international fellowship programs, etc. Be sure to have attached all certificates and/or work papers as proof of completion.

      In the event of an unfavorable assessment by the Academic Committee, you will be subjected to evaluation again in December.

      TWO CONSECUTIVE UNFAVORABLE ASSESSMENTS (JUNE AND DECEMBER) WILL RESULT IN THE CANCELLATION OF YOUR ENROLLMENT AS A Ph.D. STUDENT

      Can I join an international research visit program?

      Yes. Undertaking a period of research abroad is a requirement for Doctorado Internacional distinction eligibility. Among other requirements, your visit must have a minimum duration of three months; also, the report of activities and outcomes of your research at the host institution must be written and presented in one of the languages used for scientific dissemination in your field of research (different from any of Spain’s official languages). Prior approval by your tutor/advisor and the Academic Committee of your program is required. The Committee will evaluate your visiting research reports and, if approved, submit your candidacy for the Doctorado Internacional distinction to the Doctoral School Board.

      Thesis defense

      Biblioteca Carmen Martin Gaite

      What is a Ph.D. thesis?

      The Ph.D. thesis is the intended outcome of the doctoral training period. The thesis must give account of the student’s scientific work and meet the quality standards established by the Academic Committee of the program. Theses are defended in a public dissertation event, where they are subjected to assessment by an expert committee.

      As a general rule, Ph.D. candidates must have been enrolled on their program for a minimum period of 24 months before initiating thesis defense proceedings.

      I have approval to proceed to the thesis defense. What are the stages of this process?

      Once you get approval for your thesis defense by your tutor, advisor and Academic Committee, a minimum span of 8 weeks (excluding holiday periods) is usually required to go through these stages:

      1. Plagiarism management procedure
      2. Thesis deposit. Three weeks.
      3. Approval of thesis defense and appointment of Thesis Committee by the Dean of Doctoral School. One week.
      4. Defense session logistics. Three weeks.
      5. Thesis defense

      What is the plagiarism management procedure?

      To ensure compliance with the principles established in the Code of Good Practice for Managing Plagiarism of Ph.D. Theses of the Doctoral School, all theses must be subjected to a plagiarism management procedure prior to the authorization of the defense.

      Once the Academic Committee of your Ph.D. program determines that your research period is done and your thesis is ready for deposit, a pdf file of the thesis will be submitted to the Doctoral School to proceed to the plagiarism management.

      The results of this study will be at the disposal of the members of the thesis committee, should they be requested.

      Further information:  Plagiarism management

      What is the thesis deposit?

      The deposit of your thesis enables UC3M professors and scholars of your field to review your work before the defense. The deposit period is 15 days (excluding August), after which all comments and observations by the experts will be reported to the Academic Committee and yourself. 

      Further information:  Thesis deposit

      Who approves the defense?

      Once your thesis has successfully passed both stages, the Academic Committee of the program will elaborate their proposal for thesis defense, providing details of the proposed members of the Thesis Committee on the Authorization of thesis defense and appointment of Thesis Committee. Eligibility for “Doctorado Internacional”, “Doctorado Industrial” or International Cotutelle must be indicated, where applicable.

      This proposal will be submitted for the Dean of the Doctoral School's approval of the thesis defense and the appointment of Thesis Committee members.

      Who can be a member of the Thesis Committee?

      The Thesis Committee consists of three members (President, Secretary, and a spokesperson) and a substitute. All of them must hold a Ph.D. degree and a proven track record in research. In all cases, the Committee will be formed by a majority of members external to the University and to the institutions collaborating with the School or the Ph.D. Program.

      Further information:  Defense session. Appointment of Committee members

      How is the thesis defense organized?

      Once all authorizations are signed, the Thesis Committee’s Secretary will appoint a date for the defense. The Doctoral School Office on campus will be in charge of the logistics of the event (room reservations, technical equipment, etc.) and the travel procedures of the committee members, when applicable.

      Additionally, the Postgraduate Office will submit a digital copy of the thesis to each member of the Thesis Committee at least 15 days prior to the defense session. This file will contain any allegation or comment submitted by the experts during the deposit period.

      Further information:  Defense session. Appointment of Committee members

      Do I have to pay any fees before the defense?

      Yes. The payment of thesis defense fees must be fulfilled before proceeding to defense. Additionally, payment of enrollment fees for the academic year in which the defense takes place must be up to date.

      How is my thesis assessed?

      All Committee members must receive a copy of the thesis 15 days prior to the defense event.

      Once the Ph.D. candidate completes his/her dissertation, the Committee can provide feedback or pose questions. Their global assessment will be given in terms of Fail (No Apto), Pass (Aprobado), Good (Notable) or Excellent (Sobresaliente).

      Theses with an Excellent (Sobresaliente) grade are eligible for the cum laude distinction. The committee members will subsequently cast their votes via separate secret ballot in closed session. Only if all votes are favorable will the committee submit their proposal for the thesis to be awarded the cum laude distinction to the university Chancellor. In this case, each member of the committee will finally cast their vote, anonymously and in a sealed envelope, for the thesis to be considered for the Outstanding Thesis Award by Universidad Carlos III de Madrid.

      How can I apply for my Ph.D. certificate?

      Your application for the official Ph.D. degree certificate and the payment of the corresponding fees is done online.

      Issuance of your certificate may take a few months. Until then, you may apply for a temporary certificate as proof of completion of your Ph.D. studies as of the date of your thesis defense.

      Where is my Ph.D. thesis published?

      Your thesis will be published in e-archivo, the open online repository of Universidad Carlos III de Madrid, and Teseo the Ph.D. database managed by the Ministry of Universities. In the event of partial or temporary restrictions pertaining to the publication of your thesis, you must report them to the university.

      Glossary of terms

      Ph.D. Program. Array of training and activities oriented to the acquisition of abilities required to undertake autonomous research work in the realm of R&D. Each Ph.D. program establishes their own procedures and lines of research for the development of theses within the framework of their respective fields.

      Academic Committee. The coordinator/director of the program and two other Ph.D. members constitute a program's Academic Committee, the body in charge of the various training areas and research progress of the program, as well as the authorization of thesis defense of their Ph.D. candidates.

      Doctoral School. Academic body in charge of the management and coordination of all Ph.D. programs.

      Ph.D. Thesis. Original piece of research carried out by Ph.D. candidates in their field of knowledge. Presented as a written dissertation according to the quality, content and format guidelines set by the Ph.D. program for its public defense.

      Tutor. Supervisor in charge of tracking the training progress of the Ph.D. candidate and serving as a communication link between the researcher and the Academic Committee. Tutors must be attached to uc3m faculty with a proven research track record. Tutors are appointed upon approval of admission by the Academic Committee.

      Thesis advisor. Supervisor in charge of tracking the training progress of the Ph.D. candidate. Advisors are experts in the field of the Ph.D. candidate's research, not necessarily attached to uc3m faculty (if they are, they can also be appointed as tutors). Advisors are appointed within the first three months of the student's Ph.D. training period. A student may have more than one advisor.

      Specific training. Specific activities pertaining to the field of research of each Ph.D., designed to provide students with the knowleddge and opportunity for debate required for the development of their research work: seminars, meetings, conferences/dissertations, international research visits, etc.

      Research Skills training. Training activities oriented to the acquisition of skills common to all disciplines. All students are required to earn at least 6 credits (60 hours) throughout their doctoral training period. Enrollment on these courses is performed separately from their regular doctoral training.

      Complementary training. Maximum 40 ECTS credits. Training that the Academic Committee may deem necessary in their admission resoluction in order to complement the Ph.D. candidate's previous academic background. Enrollment on these credits will be required in addition to the student's regular doctoral training. These credits are usually earned during the first Ph.D. year. 

      Research plan. Document to be drafted within the first six months of Ph.D. training detailing the student’s research project to be subjected to annual evaluation every month of June. It must be approved by the tutor, the thesis advisor and the Academic Committee. This plan must be updated and submitted for review and evaluation purposes on a yearly basis.

      Ph.D. Activity report. A registration account of all training activities pertaining to the Ph.D. student's research. The tutor and thesis advisor must endorse these activities for them to be submitted to the Academic Committee for annual evaluation in June. 

      Student record. Academic details of every Ph.D. student as registered in uc3m databases, including activities and credits completed. This information is to be attached to the thesis in the final stages of defense approval.

      Academic transcript. Official document signed by the Head of Doctoral Studies certifying a student's academic record.

      Monitoring and assessment. Annual process by which the research progress and activities of a Ph.D. candidate are subjected to evaluation by the Academic Committee.

      Written Agreement. Document signed by all parties involved in a thesis research project (Ph.D. student, tutor, advisor/s, and Academic Committee) stating their roles and specific conditions pertaining to confidentiality agreements, copyright or use and distribution of research outcomes, where applicable, as well as conflict resolution procedures.

      Thesis public review. Procedure required to allow the academic community to review the student's thesis and issue comments and observations prior to the defense. The thesis is usually deposited at the university's intranet.

      Thesis defense. Academic event open to the public in which Ph.D. candidates defend their research work before a committee of experts in their field. The defense is followed by a question and answer session led by the defense committee in order for it to give their assessment.

      Defense committee. Committee consisting of three experts with proven track records of research in the field of the thesis, most of which must be based outside uc3m. The committee gives their assessment of the thesis and awards the cum laude distinction and the Outstanding Thesis Award candidacy, where applicable.

    • Itinerary
      Itinerario Estudiante de Doctorado
    • Regulations
    • Quality

      GENERAL INFORMATION ABOUT PH.D.

      Implementation Year: 2018-2019

      QUALITY ASSURANCE

      The Academic Committee of the Ph.D. complies with the UC3M-SGIC Internal Quallity Assurance System, which is responsible for ensuring the quality of the Ph.D. Program and produces the Degree Reports ("Memoria Académica de Titulación").

      QUALITY INDICATORS

      COMPLAINTS AND SUGGESTIONS

  • CONTACT
    Bienvenida Universidad Carlos III de Madrid

    Doctoral School Office | Leganés Campus

    Rey Pastor Building, Office 3.0.B.08
    Avenida de la Universidad, 30
    28911 Leganés (Madrid)

    Contact