In recent years the field of metaheuristics has attracted an increased interest from the research community, that has resulted in the development of new algorithms and applications in new domains. Current research has shown that the combination of different metaheuristic techniques, called hybrid metaheuristics, can improve the performance of the algorithms, specially when dealing with real-world applications. There are many application domains where the use of hybrid metaheuristics has shown to be an efficient alternative to standard methods. Real-world domains like bioinformatics, robot path planning, data mining, telecommunications, engineering, business, logistics, etc. have provided several instances of successful applications of hybrid metaheuristics.